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Stéphanie Anchisi

Head of Cell Line Development - ExcellGene

ExcellGene SA, a Swiss biologics CDMO specializing in Cell Line Development and challenging protein expression services. Single cell cloning is an essential and critical step of Cell Line Development, allowing the obtention a clonal cell line from a heterogenous pool of cells. Establishing clonality is crucial for clinical use, as it ensures consistency and reliability in downstream applications. However, without documented proof of clonality, a clonal cell line cannot be utilized in clinical settings. In light of this, ExcellGene SA relies on the Cytena Single Cell Dispenser, which offers both single cell dispensing and imaging capabilities. This technology provides documented evidence of clonality for all dispensed cells, ensuring the integrity and reliability of the resulting cell lines. The user-friendly nature of Cytena devices makes them invaluable tools for streamlining and optimizing laboratory workflows. Whether for research and development purposes or meeting CMC standards, Cytena's technology enables efficient single cells sorting and dispensing for the establishment of clonal cell lines.

Feb 13, 2024

Peter Hajdinak

Budapest University of Technology and Economics

C.BIRD is an excellent instrument for incubating suspension cells in 96/24-well plates. It prevents media evaporation and offers adequate mixing for the cells to prevent their sedimentation. Thus, it provides ideal growth conditions for the cells, increasing the experiments' reliability and reproducibility. It can simultaneously incubate and mix 3 24/96-well plates with variable mixing speeds. The instrument is controlled by a lightweight, user-friendly and easy-to-use software. The only downside of the instrument is that it needs to be connected to a PC always; it can not operate without it. CYTENA offered great after-sale care. They taught us how to use the instrument and shared some tips and tricks. Later, they also shared some relevant in-house data with us to help with our experiments. Overall, C.BIRD offers great value for its price, since you can test various media compositions in a short time, with high throughput in low volumes, to save time and money.

Apr 13, 2023